Description

oraginal Afinitor[Everolimus] for sale

Afinitor and Ibrance are both similar and different in how they treat cancer, tumors, and seizures.

Breast cancer

The Food and Drug Administration (FDA) has approved both Afinitor and Ibrance to treat advanced hormone receptor-positive, HER2-negative breast cancer in females.* However, the two drugs differ in some ways regarding their use in treating breast cancer.

Afinitor is approved for use with the anticancer drug exemestane (Aromasin) in females after menopause. The females must have already tried letrozole (Femara) or anastrozole (Arimidex), both anticancer drugs.

Ibrance is also approved to treat metastatic (advanced) breast cancer. This is breast cancer that has spread to other parts of the body. Ibrance is to be used with fulvestrant (Faslodex) in females whose cancer got worse after they tried endocrine (hormone) therapies including:

• letrozole (Femara)
• anastrozole (Arimidex)
• exemestane (Aromasin)

Ibrance is also approved as the starting therapy for advanced or metastatic breast cancer in either females who have gone through menopause or males.* Ibrance is to be used with an aromatase inhibitor (AI). AIs are a type of hormone therapy that blocks the production of estrogen.

Other cancers and tumors

While Ibrance is only approved to treat breast cancer, Afinitor is approved to treat other cancers and tumors including:

• advanced renal cell carcinoma (kidney cancer) in adults who have already tried the anticancer drugs sunitinib (Sutent) or sorafenib (Nexavar)
• neuroendocrine tumors in the pancreas, lung, or stomach/gut in adults that can’t be treated with surgery
• renal angiomyolipoma, a type of benign (not cancerous) kidney tumor in adults with the genetic disorder tuberous sclerosis
• subependymal giant cell astrocytoma (SEGA), a type of benign (not cancerous) brain tumor in adults or children ages 1 year and older with tuberous sclerosis (Afinitor Disperz is also approved to treat these brain tumors.)

Partial seizures

Afinitor Disperz is approved for use with antiseizure drugs to treat partial seizures(also called focal onset seizures) in:

• adults and children ages 2 years and older with tuberous sclerosis

Drug forms and administration

Afinitor is available in two forms:

• Afinitor. This comes as a tablet that you swallow. Be sure to take Afinitor tablets whole. Don’t chew, split, or crush them. The tablets come in four strengths:
  • 2.5 mg
  • 5 mg
  • 7.5 mg
  • 10 mg
• Afinitor Disperz. This comes asa tablet that you must prepare as an oral suspension. This means you’ll dissolve it in water, which you then swallow. The tablets come in three strengths:
  • 2 mg
  • 3 mg
  • 5 mg

Ibrance comes as capsules and tablets that you swallow. It’s available in three strengths:

• 75 mg
• 100 mg
• 125 mg